Журнал инфекционных заболеваний и терапии

Абстрактный

A look into Possible New Treatment Modality for COVID 19: ACE 2

Mayank Kapoor

Many articles about COVID 19 have mentioned various experimental drugs but nowhere it has been mentioned about any new research on ACE 2 (Angiotensin converting enzyme 2), which is a receptor for coronavirus, in the direction of curbing it. Hereby a logically deduced & scientific study backed analysis of a group of drugs affecting the ACE2 system is presented. ACE2 is an integral part of the pathogenic mechanisms & disease progression of COVID-19 & up regulation of ACE2 levels leads to significant reduction in morbidity & mortality of ARDS. SARSCoV- 2 binds to & down regulates this protective ACE2 & thus leads to the acute lung injury associated with it. Hence ACE 2 up regulation maybe the way to defeat this pandemic which has the whole of humanity in its grip.