Журнал беременности и здоровья детей

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Acute Fatty Liver of Pregnancy: A Case Report and Literature Review

Nilanchali Singh and Pragati Meena

Acute Fatty Liver of Pregnancy (AFLP) is a rare, catastrophic disease affecting women in pregnancy. It usually occurs in the third trimester or post-partum period. It is usually a diagnosis of exclusion and a strong index of suspicion can lead to timely diagnosis. Delay in diagnosis is associated with morbid complications with high mortality. We report a case of 22 years old lady with 36 weeks pregnancy presented with malaise, nausea, vomiting and jaundice. A clinical diagnosis of acute fatty liver of pregnancy was made. Although early Cesarean section was performed, postoperative course was complicated by acute hepatic encephalopathy with hepatorenal shutdown and coagulopathy. Despite intensive management in critical care, the patient expired.