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Aden carcinoma NOS of The Maxillary Sinus: Clinical and Histopathological Features with Therapeutic Considerations

Angela Santoro

Malignant tumors of the nasal cavities and paranasal sinuses are uncommon. They constitute less than one per cent of all tumours and less than three per cent of head and neck tumours. Carcinoma of the maxillary sinus is the most common of the sinonasal malignancies. In this anatomical site a case of adenocarcinoma, not otherwise specified, was documented, mainly from a histological perspective and discussed considering all types of differential diagnoses. Keywords: Adenocarcinoma NOS; Immunohistochemistry; Differential diagnosis Adenocarcinoma not otherwise specified (NOS), is a malignant epithelial salivary gland tumor with glandular or ductal adenocarcinomatous differentiation but without other specific histologic features, allowing for a more definitive classification and that characterize the other defined types of salivary carcinoma. The modifying term “not otherwise specified” should be included because most other epithelial salivary gland malignancies are also adenocarcinomas Case Report A 65- year-old Italian woman was referred to the “Clinica Odontoiatrica” of the Second University of Naples, Napoli (Italy) complaining of swelling in the right upper edentulous molar area and fornix. A recent study has identified the role of work exposure to organic dusts in patients with malignant paranasal sinus tumors .