Журнал болезни Альцгеймера и паркинсонизма

Абстрактный

Alzheimer's Disease and Memory Loss - A Review

Naresh Korrapati and Naga Pavan Kumar B

Memory loss is one of the first symptoms in patients suffering from Alzheimer’s disease (AD). During the course of the disease patients experience problems with their language, mood swings, and behavioural issues. Due to these conditions patients often withdraw from family or society with the fear and embarrassment and gradually, bodily functions are lost leading to death. The pattern of memory loss correlates with structural and functional integrity of brain. In patients with AD the formation of memory will be affected at molecular level disturbing the framework of neural networks. Recently, many studies have focused on how the AD impacts episodic memory and the underlying neural processes. In this review the findings of these studies are discussed and the effects of current and promising treatments for AD on memory loss are summarized. The main aim of this review is creating awareness in understanding the intact and dysfunctional memory. Moreover the knowledge of a specific process of a particular memory loss due to AD helps the basic scientists in developing novel therapies and drugs.