Журнал молекулярной фармацевтики и исследований органических процессов

Абстрактный

An Organized Method for Drug Discovery Using Plant Sources

Reza Amani

The combination of declining figures of new medicine blessings and rising prohibitive costs poses serious challenges to medicine discovery. The arrival of combinatorial chemistry has given rise to renewed stopgap of adding the success rate of new chemical realities (NCEs). But indeed this scientific development has not bettered the success rate of new medicine discovery. This script has allowed us to develop a new approach to integrated medicine discovery where Ayurvedic wisdom can interact with medicine discovery from botanical sources. The first step in medicine discovery involves NCE identification. NCEs can be attained by chemical conflation or insulated from natural products by biologically active separation. The source of numerous new medicines and active constituents in medicinal comes from natural products. A starting point for discovering new factory- grounded drugs is to use Ayurvedic wisdom, traditional proved uses, undocumented ethnical uses, and expansive literature review to identify suitable campaigners. A frequence analysis of the factors of recently proved phrasings and an analysis of their Ayurvedic parcels will allow the selection of suitable seeker shops for separation grounded on their natural exertion. We can give you a complete idea about the dominance of Vedic parcels. Integrating the wisdom of Ayurveda into pharmaceutical exploration requires a paradigm shift in the birth process from successional to resembling birth. Bioassay- grounded separation of linked shops yields formalized excerpts or insulated bioactive medicinal composites as new medicines. This integrated approach improves medicine discovery success rates and saves cost and time.