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Atherosclerosis : An Overview

Negar Salehi

Atherosclerosis is the narrowing of arteries due to plaque buildup on the artery walls. Arteries carry blood from the heart to the rest of the body. A thin layer of cells forms a lining that keeps them smooth and allows blood to flow easily. This is called the endothelium. Atherosclerosis happens when the endothelium becomes damaged, due to factors such as smoking, high blood pressure, or high levels of glucose, fat, and cholesterol in the blood. This damage allows a collection of substances, known as plaque, to build up in the artery wall. These substances include fat and cholesterol.