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Canaglifozin in the Diabetic-Obese and Poorly Controlled

Pedro J Tárraga López, Fatima Madrona Marcos, Loreto Tarraga Marcos, Carmen Celada Roldan, Juan Solera Albero, Jose Luis Castro Navarro, Raul Salmeron Rios, Angel Celada, Ibrahim Sadek and JJ Atienza

Objective: To analyze the metabolic evolution in patients with previous poor control after starting treatment with canagliflozin.
Methodology: A retrospective observational study in patients with poor glycemic control assigned to several health centers of Albacete and Cuenca provinces in which treatment with canagliflozin has been started after 6 months. Variables are analyzed: age, sex, weight, height, BMI. Analytical variables: glycemia, glycated hemoglobin, total cholesterol, HDL, LDL, triglycerides, uric acid, C-reactive protein, urea, creatinine proteinuria
Results: 107 diabetic patients participated, 45.5% men, Average age 61, 16-23 years. Basal variable 6 months level signify Glucemia fasting 157.41-126.89, p>0.002 Hemoglobin glycated 8.55-6.91, p>0.003, Weight 84.31-80.21, p>0.002, BMI 31.66-30.04, p>0.04, Cholesterol T 199.05-188.61, p>0.03, LDL 113.36-97.102, p>0.05, TG 195.18-176.80, p>0.05.
Conclusion: The treatment with Canaglifozin 100 has been effective for the metabolic control of patients previously poorly controlled.