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COVID-19 and the Angiotensin-Converting Enzyme 1 D/I Genotype: Protection of People at High-Risk by Predicting the Severity of the Disease

Naoki Yamamoto

Throughout history, humans have been threatened by various infectious diseases. As of August 22, 2020, a new coronavirus infection, COVID-19, has been raging around the world, infecting approximately 23 million people and killing approximately 800,000. Although COVID-19 is a serious infectious disease, it is at most comparable to the 1968 Hong Kong flu given the far more deaths caused by previous devastations, such as the plague, smallpox, Spanish flu, AIDS, tuberculosis and malaria. However, we are still in the midst of the epidemic, and it is difficult to project the extent of damage COVID-19 will ultimately inflict.