Отчеты о трансплантации: открытый доступ

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COVID-19 Burden in Patients with Excretory Organ Transplants is Affected by Hypertension

Fang Wang

Background: COVID-19 severity is set by cardio metabolic risk factors, which could be additional aggravated by chronic disorder in internal organ transplant recipients (KTRs). we've an inclination to aimed to verify the foremost risk factors related to high force per unit area (HTN) that contribute to COVID-19 progression and mortality in that population. Methods: Retrospective analysis of 300 KTRs from March 2020 to August 2020 in a {very} very single center. We’ve an inclination to compared the foremost outcomes between HTN (n = 225) and non-HTN (n = 75), furthermore as admission to the medical care unit (ICU), development of acute internal organ injury (AKI), would really like for invasive mechanical ventilation or O, and mortality. Results: Of the patients inside the study, 57.3% were male, 61.3% were white, and the mean age was fifty 2.5 years, and seventy fifth had HTN. Pre-existing HTN was severally associated with higher rates of mortality (32.9%, OR = 1.96, p = 0.036), transfer to the ICU (50.7%, OR = 1.94, p = 0.017), and AKI with qualitative analysis (HD) demand (40.4%, OR = 2.15, p = 0.011). Inside the hypertensive cluster, age, diabetes, upset, smoking, glycaemic management before admission, globulin, suckle dehydrogenase, lymphocytes, and D-dimer were significantly associated with COVID-19 progression and mortality. Every lower basal and former denumerable capillary filtration rates show KTRs with HTN at larger risk for HD demand. Conclusions: therefore, the primary identification of things that predict COVID-19 progression and mortality in KTRs stricken by COVID-19 contributes to therapeutic choices, patient flow management, and allocation of resources [1].