Журнал цитокиновой биологии

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Cytokine Release Syndrome: Unravelling the Complex Immune Response

Abhinav Verma

Cytokine Release Syndrome (CRS) is a complex and potentially life-threatening immune response characterized by the excessive release of cytokines in the body. This article explores the causes, symptoms, and treatment options for CRS, highlighting its significance in the context of modern medicine. CRS is often associated with immunotherapies, infections, autoimmune diseases, and certain medications. Its symptoms range from mild to severe, including fever, fatigue, and multi-organ dysfunction. Treatment strategies encompass supportive care, immunosuppression, cytokine-targeted therapies, and extracorporeal treatments. Understanding CRS is crucial for advancing immunotherapy and managing autoimmune diseases, emphasizing the delicate balance of the immune system.