Журнал инфекционных заболеваний и терапии

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Determination of the Diagnosis of Non-Tuberculous Mycobacterial Infections by Metagenomic Next-Generation Sequencing

He Zhu and Limin Zhao

Non-Tuberculous Mycobacteria (NTM) is ubiquitousin the environment and is conditional pathogen. Due to NTM and Mycobacterium tuberculosis belong to the genus Mycobacterium, their pathogenic mechanisms and clinical manifestations are similar. Therefore, NTM can cause tuberculosis-like lesions and lead to misdiagnosis. Early diagnosis and treatment greatly improve prognosis. However, traditional pathogenic microorganism detection has limitations, and it is difficult to accurately identify strains in clinical practice. In this editorial，We summarize the diagnosis and treatment of NTM, and the unique advantages of metagenomic next-generation sequencing in the identification of pathogenic microorganisms.