Журнал клеточной и молекулярной фармакологии

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Enzyme Kinetics in Drug Discovery Accelerating Therapeutic Innovation

Daisuke Nakanishi*

Enzyme kinetics is a fundamental discipline within biochemistry that has emerged as a key player in revolutionizing drug discovery. This article explores the pivotal role of enzyme kinetics in accelerating therapeutic innovation. The molecular dance between enzymes and substrates provides critical insights into reaction mechanisms, substrate specificity, and catalytic efficiency. Leveraging these insights, researchers can design drugs with unparalleled precision, leading to the development of targeted and effective therapeutic interventions. The article discusses how enzyme kinetics expedites the drug discovery process, from optimizing drug formulations to dissecting complex biological pathways. Furthermore, it highlights the synergy between experimental and computational approaches, paving the way for a new era of precision medicine. The journey from bench to bedside is illuminated, emphasizing the translation of kinetic discoveries into tangible therapeutic solutions. Finally, the article glimpses into the future, where emerging technologies promise to propel enzyme kinetics into new frontiers, fostering continued acceleration in therapeutic innovation