Журнал молекулярной фармацевтики и исследований органических процессов

Абстрактный

Evaluating the Photosensitivity of the Chinese Chlorella on Red Blood Cells

Fedda Y Alzoubi, M-Ali AL-Akhras, Hesham A Al-Omari and Khaled Aljarrh

The photosensitivity of the Chinese Chlorella (CC) which is a natural algae is investigated by considering its ability of killing red blood cells when their mixture exposed to light. Different experimental studies were performed to figure out the photohemolysis rate of red blood cells mixed with different concentrations of the Chinese Chlorella at different temperatures and irradiation times. Photohemolysis curves are obtained using different approaches: the continuous and delayed irradiations. All obtained data were fitted to the Gompartz function and results showed that the photohemolysis rate increases as the temperature as well as the concentration of the Chinese Chlorella increases. In general, Chinese Chlorella represents a good candidate for a photosensitive material that can be used in photodynamic therapy.