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Free-Breathing Hepatobiliary Phase Gd-EOB-DTPA-Enhanced MR Imaging with Radial VIBE Sequence: Comparison with Conventional Cartesian VIBE Sequence

Sasaki M, Fukukura Y*, Kumagae Y, Iwanaga T, Saito T, Imai H, Saigo Y and Yoshiura T

Purpose: To assess the feasibility of three-dimensional fat-suppressed T1-weighted gradient-echo sequence with radial volumetric interpolated breath-hold examination (rVIBE) compared with that of conventional Cartesian VIBE (cVIBE) sequence for free-breathing hepatobiliary phase of gadolinium-ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MR imaging and to investigate the optimal number of radial views for rVIBE.

Methods: Thirty patients who underwent hepatobiliary phase Gd-EOB-DTPA-enhanced MR imaging with freebreathing cVIBE and rVIBE sequences using radial views of 256 (rVIBE256), 512 (rVIBE512), and 1024 (rVIBE1024) for the evaluation of suspected liver tumors were enrolled in our study. Signal-to-noise ratios (SNRs) of the liver and image quality were compared between cVIBE and rVIBE sequences using the Steel-Dwass test of post hoc nonparametric multiple comparisons.

Results: SNR of the liver was significantly higher for rVIBE with all three radial views than for cVIBE (all, P<0.001). The rVIBE256 showed a significantly lower SNR than rVIBE512 (P=0.004) and rVIBE1024 (P<0.001), but no significant difference was obtained between rVIBE512 and rVIBE1024 (P=0.122). The overall image quality was significantly higher for all rVIBE radial views than for cVIBE (all, P<0.001). The mean score of overall image quality was significantly lower for rVIBE256 than for rVIBE512 and rVIBE1024 (both, P<0.001), and there was no significant difference between rVIBE512 and rVIBE1024 (P=0.902).

Conclusions: Our study suggests that rVIBE512 is more feasible in patients with diminished respiratory capacity in the hepatobiliary phase of Gd-EOB-DTPA-enhanced MR imaging.