Журнал диабета и клинической практики

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Immunohistochemistry (IHC)

Anukul CM

Immunohistochemistry (IHC) is a vital technique used in pathology and research to identify and visualize specific proteins or antigens within tissue samples. This powerful method combines principles of immunology and histology, enabling researchers and clinicians to gain valuable insights into tissue biology. The process involves using specific antibodies labeled with detectable markers to bind to target proteins in tissue sections. IHC plays a significant role in disease diagnosis, biomarker discovery, and drug development, as it allows for accurate identification of biomarkers and protein expression patterns. This short note provides an overview of the principles, procedure, and significance of Immunohistochemistry in advancing our understanding of various diseases and biological processes.