Журнал онкологических исследований и лечения

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Improving Precision in Prognostication for the Elderly Population with Follicular Lymphoma

Tan Jiao Jie Cherie, Clarice Choong Shi Hui

Follicular Lymphoma (FL) remains a highly heterogeneous entity with various outcomes. In some patients, the disease exhibits aggressive and chemotherapy-resistant behavior. On the other hand, the disease remains indolent with durable remissions after initial treatment.

Such complexity in risk-stratifying patients is more so important in elderly patients with FL where early detection of the progression of the disease can lead to early treatment and prolongation of the quality of life.

Several studies suggest that disease recurrence within 2 years of first-line treatment of FL occurs consistently in as many as 20% of patients independent of maintenance rituximab.