Журнал клинической и экспериментальной трансплантации

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Infectious Complications in Organ Transplantation: Strategies for Care

Constine L

Organ transplantation has revolutionized modern medicine, providing life-saving options for patients with endstage organ failure. However, this medical marvel is not without its challenges, and one of the most significant hurdles faced by transplant recipients is the risk of infectious complications. This abstract provides an overview of key strategies for managing and preventing infectious complications in organ transplantation. The success of organ transplantation relies on the careful balance between suppressing the recipient’s immune system to prevent organ rejection and maintaining a sufficiently robust immune response to ward off infections. Consequently, transplant recipients are susceptible to a wide range of infectious agents, including bacteria, viruses, fungi, and parasites. These infections can manifest at various stages post-transplantation, with varying degrees of severity, and pose a significant threat to both graft and patient survival. This abstract highlights the multifaceted approach required to address infectious complications in organ transplantation. It discusses the importance of pre-transplant screening and risk assessment, as well as the selection of immunosuppressive regimens tailored to individual patient profiles. The role of vaccination in preventing opportunistic infections is emphasized, along with the ongoing need for vigilant monitoring and early detection of infectious threats. Moreover, the abstract explores emerging diagnostic techniques and therapeutic interventions, such as antimicrobial stewardship programs, that have the potential to enhance patient care and reduce the burden of infectious complications. The importance of interdisciplinary collaboration among transplant surgeons, infectious disease specialists, pharmacists, and microbiologists is underscored to ensure comprehensive care.