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Metastatic Choriocarcinoma of the Kidney in Absence of Existing Primary Uterine Tumour: A Rare Presentation

Saloni Pahwa, Sharma Anila, Kamboj Meenakshi, Gupta Gurudutt, Pasricha Sunil

Gestational choriocarcinomas are malignant neoplasms generally arising in the uterus in women of child bearing age. These are aggressive tumours with high incidence of metastasis to vascular organs like lung, liver and brain. Renal metastasis is extremely rare with low incidence rate and very few cases reported in literature. Hereby, we report a rare case of metastatic choriocarcinoma to the kidney in a 29 year old female 10 years after resection of a Hydatidiform mole. The histopathological diagnosis was made on a nephrectomy specimen. Pelvic and abdominal scan did not show any abnormal radiological findings. She was started on first line chemotherapy and showed complete response. In conclusion, gestational or primary non-gestational choriocarcinomas should always be considered as a differential diagnosis in young females of reproductive age group presenting with flank abdominal pain, unexplained hematuria and atypical renal tumour histology.