Журнал клеточной и молекулярной фармакологии

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Molecular Docking and Drug Repurposing Finding New Uses for Old Drugs

Raadan Konnai

This article explores the fascinating intersection of molecular docking and drug repurposing, showcasing how old drugs can find new life in alternative therapeutic applications. Drug repurposing, or repositioning, is gaining momentum as a cost-effective and time-efficient strategy to discover novel medical treatments. Molecular docking, a computational technique, plays a pivotal role in this process by enabling the study of ligand-receptor interactions and predicting binding affinities. Case studies highlight successful drug repurposing initiatives, emphasizing the role of molecular docking in uncovering these new applications. Challenges and prospects in the field are also discussed, underscoring the ongoing synergy between computational techniques and experimental validation. As the pharmaceutical industry evolves, the synergy between molecular docking and drug repurposing promises to expedite innovative therapy development, benefiting patients and reducing costs