Журнал клинической и экспериментальной патологии

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Overview on Peutz-Jegher Syndrome in Gynecologic Pathology

Ozlen Saglam*

Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant disorder characterized by melanotic macules, intestinal polyps, and an increased cancer risk [1]. There are diverse pathologic manifestations of the syndrome in females. These can present from early infancy to late adulthood either concomitantly or subsequently. There is no consensus or guidelines for cancer surveillance in PJS patients. There are occasions when the pathologist’s awareness and interpretation of the microscopic findings can contribute to the overall clinical managements of these cases.