Клинические инфекционные заболевания и практика

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Red Blood Cells: Key Contributors in HIV Infection and Disease Modulation

Hartman Amy

Red blood cells (RBCs), also known as erythrocytes, are the most abundant cells in our bloodstream. Their primary function is to transport oxygen to tissues and remove carbon dioxide, ensuring the body's overall oxygenation. However, recent research has shed light on the remarkable role of RBCs beyond their traditional function. Scientists have discovered that RBCs play a critical role in both enhancing and preventing HIV infection and other diseases. This article explores the fascinating mechanisms through which RBCs contribute to these processes.

The group reached consensus on the prevalence of anemia in the highly active antiretroviral therapy era; the risk factors that are independently associated with the development of anemia; the impact of anemia on quality of life, physical functioning, and survival; the impact of the treatment of hepatitis C virus coinfection on anemia in HIV-infected patients; evidence-based guidelines for treatment of anemia in HIV-infected patients, including the therapeutic role of epoetin alfa and directions for future research.