Журнал клеточной и молекулярной фармакологии

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Rising to the Challenge Confronting Drug Resistance in the Modern Healthcare Landscape

Hattersley Larralde

Drug resistance has emerged as a formidable challenge in modern healthcare, posing significant threats to the effectiveness of treatments across various medical disciplines. This paper examines the multifaceted problem of drug resistance, encompassing its molecular mechanisms, epidemiological factors, and clinical implications. We delve into the pivotal role of microbial organisms, such as bacteria and viruses, in driving antibiotic and antiviral resistance, as well as the genetic and adaptive processes that underlie this phenomenon. Furthermore, we explore how drug resistance extends beyond infectious diseases to encompass cancer and other non-communicable diseases, complicating therapeutic strategies. The socio-economic dimensions of drug resistance are also considered, highlighting the economic burdens and healthcare disparities it engenders. In response, this paper proposes a comprehensive approach involving enhanced surveillance, novel drug development, optimized treatment protocols, and public education. By rising to the challenge of drug resistance, the modern healthcare landscape can safeguard the efficacy of existing treatments and ensure better health outcomes for patients worldwide.