Журнал терапии ожирения и снижения веса

Абстрактный

Short-term Effects of Supplementation with a Multi-ingredient Weight-loss Product on Weight Maintenance and Fat Oxidation in Obese Female with Weight Reduction: Preliminary Results

Naoki Sakane, Kazuhiko Kotani, Kokoro Tsuzaki, Kaoru Takahashi, Narumi Nagai, Toshio Moritani, Kahori Egawa, Makiko Yoshimura, Yoshihinori Kitagawa and Hiroshi Shibata

Background: Numerous multi-ingredient weight-loss supplementation products are marketed, whereas the effects of these supplements on weight maintenance have rarely been studied. This study aimed to investigate preliminarily whether a 4-week supplementation of a multi-ingredient weight-loss product (named ‘diet’s BB’), containing L-carnitine, banaba, caffeine, capsaicin, Nelumbo nucifera leaf extract and sesamin, could contribute to weight maintenance and its related parameters among obese women with weight reduction following a Low-calorie Diet (LCD). Methods: In a prospective, randomized, double-blind intervention design, subjects with ≥5% of weight reduction following LCD were randomized to the group who used the diet’s BB (Group A) or tablet containing six types of vitamins (Group B) for four weeks. Their body weight and related parameters, including Respiratory Quotient (RQ) and fat oxidation, were measured pre- and post-intervention. Results: The changes in body weight and related parameters were not significantly different between the groups. Group A showed significantly reduced RQ and increased fat oxidation more than the Group B. Conclusion: The short-term multi-ingredient weight-loss supplementation product did not yield further weightloss for obese women with weight reduction, while it could potentially lead to favorable changes of fat oxidation levels. The effects of the supplementation on weight traits merit large-scale and long-term investigations.