Журнал гигиены полости рта и здоровья

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Stomatitis Medicamentosa: A Case Report with Review

Pravda C, Raghu Ganesh and Koteeswaran

A great variety of drugs are implicated in oral mucosal lesions. Allergic inflammatory reactions of oral mucosa due to intake of drug are rare and non-specific. These reactions are found to be associated with drug or medicament used locally or systemically. An allergic reaction from topical medications is referred as Stomatitis venenata. Stomatitis medicamentosa is a less common oral lesion that is produced with systemic administration of drugs. The lesion may vary from diffused distribution of erythema to extensive areas of ulcerations with or without vesicle or bulla formation. The lesions are seen commonly involving gingiva, palate, lips and tongue.

This article includes a case of Stomatitis medicamatosa in a patient who presented with multiple oral ulcerations on oral administration of Carbamazepine used for the treatment of Trigeminal Neuralgia. The article also includes a review of other oral reactions that are associated with systemic administration of various other drugs.