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The Prevalence and Risk Factors for Acute Renal Damage during Esophageal Cancer Surgery

Lee Chung

Postoperative complications like acute kidney injury (AKI) are becoming more and more common. Postoperative acute kidney injury (AKI) following thoracic surgery has been the subject of numerous studies, but little is known about AKI following esophageal surgery. As a result, we conducted this research to ascertain the prevalence and risk factors of AKI postoperatively following esophageal cancer surgery. Methods and Materials: Patients who underwent elective esophageal cancer surgery in a single tertiary specialized cancer hospital between July 2013 and July 2016 were the subjects of a nested case-control study. The development of AKI was the primary outcome. Independent risk factors for acute kidney injury (AKI) were identified using conditional logistic regression analysis. After esophageal cancer surgery, 51 (2.4%) of 2094 patients experienced postoperative AKI. Four risk factors for acute kidney injury (AKI) following cancer esophageal surgery were identified using multivariate conditional logistic regression analysis: Level of serum creatinine prior to surgery, length of surgery, and prior history of smoking (OR 3.029; Postoperative acute kidney injury (AKI) occurred in 2.4% of cancer patients who underwent esophageal surgery (95% CI: 1.092–8.399) and hypertension. Independent risk factors for postoperative acute kidney injury (AKI) included the preoperative serum creatinine level, surgery duration, smoking history, and hypertension