Журнал клинического диабета

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Transgenic Fluorescent Rat with Simultaneous 3-Dimensional Cellular Location and Terminal Neuronal Characteristics

Kali Yug

The development of transgenic animal models has revolutionized scientific research, particularly in the field of neuroscience. In this regard, a recent breakthrough involves the creation of a transgenic fluorescent rat model capable of simultaneous visualization of both cellular location and terminal neuronal characteristics in a threedimensional context. This model allows for the tracking and visualization of specific cell types within the rat’s body, providing insights into dynamic processes such as cell migration and tissue development. Additionally, the model facilitates the study of individual neurons, their dendritic arborisations, and axonal projections, shedding light on the complex neural circuitry underlying behavior and cognition. The transgenic fluorescent rat model holds significant potential for advancing our understanding of neurological disorders and conditions, facilitating the development of novel therapeutic approaches, and finding applications in other fields such as developmental biology and toxicology. This remarkable scientific advancement represents a powerful tool for unraveling the complexities of the brain and driving future scientific breakthroughs.