Журнал клинической и экспериментальной трансплантации

Абстрактный

Transplantation Transformation: Harnessing Cellular Therapies

Wang G

The field of transplantation medicine has witnessed remarkable advancements in recent years, driven by the emergence of cellular therapies. This abstract provides an overview of the transformative potential of cellular therapies in the context of transplantation. Cellular therapies represent a paradigm shift in the management of organ transplantation, offering a promising alternative to traditional transplantation methods. This abstract highlights key aspects of cellular therapies, including their mechanisms of action, applications, and potential benefits. First, the abstract discusses the fundamental principles underlying cellular therapies. These therapies involve the isolation, expansion, and manipulation of specific cell types, such as mesenchymal stem cells, regulatory T cells, and induced pluripotent stem cells. These cells can be utilized to modulate the immune system, repair damaged tissues, and induce transplant tolerance. Next, the abstract explores the diverse applications of cellular therapies in transplantation. From enhancing graft survival to reducing the reliance on immunosuppressive drugs, cellular therapies offer a versatile toolkit for transplant clinicians. Moreover, they hold promise for regenerative medicine approaches, allowing the repair and regeneration of injured or degenerated organs. Furthermore, this abstract delves into the potential benefits of cellular therapies. By reducing graft rejection rates, minimizing complications, and improving long-term outcomes, cellular therapies have the potential to revolutionize transplantation outcomes. Additionally, the mitigation of transplant-related morbidities and the prospect of personalized medicine approaches contribute to the allure of cellular therapies.