Желудочно-кишечная и пищеварительная система

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Updates in Drug Development Strategies against Peptic ulcer

BB Subudhi, SP Sahoo, PK Sahu

Traditional use of antacids and use of histamine inhibitors have become ineffective in the management of peptic ulcer. Irreversible inhibition of proton pump although reduces ulceration, in the long run leads to adverse issues. It has not been possible to develop an ideal proton pump inhibitor. In this scenario, search for alternatives by capitalizing on the multifactorial etiology of ulceration holds promise.